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65-46-3

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Identification

Name
Cytidine
CAS
65-46-3
Synonyms
CYTIDINE HYDROCHLORIDE
1beta-D-Ribofuranosylcytosine
1-beta-ribofuranosylcytosine
1beta-Ribofuranosylcytosine
2(1H)-Pyrimidinone, 4-amino-1-beta-D-ribofuranosyl-
4-amino-1-beta-d-ribofuranosyl-2(1h)-pyrimidinon
beta-D-Ribofuranoside, cytosine-1
Cyd
Cytidin
Cytosine, 1-beta-D-ribofuranosyl-
Cytosine β-D-riboside
Cytosine-1-β-D-ribofuranoside
CYTIDINE FREE BASE CELL CULTURE TESTED
Cytosine-1-β-D-ribofuranos
CytidineForBiochemistry
Cytidene,>98%
4-Amino-L-β-D-ribofuranosyl-2-[1H]-pyrimidinone
Citidine
Cytidine, 99+%
CYTIDINE(Cytosine-1--D-ribofuranoside)
EINECS(EC#)
200-610-9
Molecular Formula
C9H13N3O5
MDL Number
MFCD02181091
Molecular Weight
243.22
MOL File
65-46-3.mol

Chemical Properties

Appearance
White crystalline powder
Melting point 
210-220 °C (dec.) (lit.)
mp 
210-220 °C (dec.)(lit.)

alpha 
31.5 º (c=0.6, H2O 25 ºC)
Boiling point 
386.09°C (rough estimate)
density 
1.3686 (rough estimate)
refractive index 
34 ° (C=0.7, H2O)
storage temp. 
Store at RT.
solubility 
H2O: 50 mg/mL

pka
4.22, 12.5(at 25℃)
form 
powder

color 
White to almost white
Stability:
Stable. Incompatible with strong oxidizing agents. Protect from moisture.
optical activity
[α]20/D +33°, c = 2 in H2O
Water Solubility 
SOLUBLE
Sensitive 
Hygroscopic
Merck 
14,2786
BRN 
89173
CAS DataBase Reference
65-46-3(CAS DataBase Reference)
NIST Chemistry Reference
Cytidine(65-46-3)
EPA Substance Registry System
65-46-3(EPA Substance)

Safety Data

Risk Statements 
R68:Possible risk of irreversible effects.
Safety Statements 
S24/25:Avoid contact with skin and eyes .
WGK Germany 
3

RTECS 
UW7370000


10-23
TSCA 
Yes
HS Code 
29349900
Toxicity
LD50 intraperitoneal in mouse: 2700mg/kg

Raw materials And Preparation Products

Hazard Information

General Description
White crystalline powder.
Reactivity Profile
CYTIDINE(65-46-3) is incompatible with strong oxidizing agents. . Will react as a weak base.
Air & Water Reactions
This compound is hygroscopic. Water soluble.
Fire Hazard
Flash point data for this compound are not available; however, CYTIDINE is probably combustible.
Description
Cytidine is a pyrimidine nucleoside that is composed of the pyrimidine base cytosine attached to the sugar ribose. As a constituent of RNA, cytidine pairs with guanine, and it is a precursor of uridine. Cytidine can incur several modifications in mRNA, including methylation and acetylation, that function to regulate translation. Cytidine can also be formylated to 5-formylcytidine in mitochondrial methionine transfer RNA (tRNAMet).
Chemical Properties
White crystalline powder
Uses
increases cell membrane phospholipids
Uses
Cytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring, cytidine is a component of RNA.
Uses
A constituent of nucleic acids. It was isolated from yeast nucleic acid.
Definition
A NUCLEOSIDE formed when cytosine is linked to D-ribose via a β-glycosidic bond.
Definition
ChEBI: A pyrimidine nucleoside in which cytosine is attached to ribofuranose via a beta-N1-glycosidic bond.
Definition
cytidine: A nucleoside comprisingone cytosine molecule linked to a dribosesugar molecule. The derivednucleotides, cytidine mono-, di-, andtriphosphate (CMP, CDP, and CTP respectively)participate in various biochemicalreactions, notably inphospholipid synthesis.
Purification Methods
Cytidine crystallises from 90% aqueous EtOH. It has also been converted to sulfate by dissolving (~200mg) in a solution of EtOH (10mL) containing H2SO4 (50mg), whereby the salt crystallises out. It is collected, washed with EtOH and dried for 5hours at 120o/0.1mm. The sulfate has m 225o. The free base is obtained by shaking the salt solution with a weak ion-exchange resin, filtering, evaporating and recrystallising the residue from EtOH as before. [Fox & Goodman J Am Chem Soc 73 3256 1956, Fox & Shugar Biochim Biophys Acta 9 369 1952; see Prytsas & Sorm in Synthetic Procedures in Nucleic Acid Chemistry (Zorbach & Tipson Eds) Vol 1 404 1973.] [Beilstein 25 III/IV 3667.]

Material Safety Data Sheet(MSDS)

msds information
Cytidine(65-46-3).msds

Spectrum Detail

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