Identification Chemical Properties Safety Data Hazard Information Spectrum Detail Well-known Reagent Company Product Information Supplier Related Products

64-77-7

Name TOLBUTAMIDE
CAS 64-77-7
EINECS(EC#) 200-594-3
Molecular Formula C12H18N2O3S
MDL Number MFCD00027169
Molecular Weight 270.35
MOL File 64-77-7.mol

Chemical Properties

Appearance white crystalline powder
Melting point  128-130°C
density  1.2450
refractive index  1.6360 (estimate)
storage temp.  Sealed in dry,Room Temperature
solubility  Soluble in chloroform.
form  neat
pka pKa 5.32(H2O t = 37) (Uncertain)
color  White to Off-White
Stability: Stable. Combustible.
Water Solubility  0.14g/L(25 ºC)
Merck  14,9507
BRN  1984428
Concentration 0.1 mCi/ml
Solvent Ethanol
Specific Activity 50-60 mCi/mmol
CAS DataBase Reference 64-77-7(CAS DataBase Reference)
EPA Substance Registry System Tolbutamide (64-77-7)

Safety Data

Hazard Codes  F,Xn
Risk Statements 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R40:Limited evidence of a carcinogenic effect.
R43:May cause sensitization by skin contact.
Safety Statements 
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
WGK Germany  2
RTECS  YS4550000
TSCA  Yes
HS Code  29350090
Safety Profile
Moderately toxic by ingestion and several other routes. A human teratogen. Human reproductive effects by ingestion and possibly other routes: stillbirth, developmental abnormalities of the cardlovascular (circulatory) system and urogenital system, and unspecified neonatal effects. Human systemic effects by ingestion: nausea or vomiting, hypoglycemia. Other experimental teratogenic and reproductive effects. Mutation data reported. Implicated in aplastic anemia. When heated to decomposition it emits very toxic fumes of NO, and SOx.
Hazardous Substances Data 64-77-7(Hazardous Substances Data)
Toxicity
LD50 oral in rat: 2490mg/kg

Hazard Information

Well-known Reagent Company Product Information

Supplier