Chemical Properties
Colorless liquid; pleasant odor; sweet
taste.Soluble in alcohol and ether;
insoluble in water.
General Description
A clear colorless liquid with a pleasant odor. Flash point 50°F. Prolonged exposure to fire or heat may cause vigorous decomposition and rupturing of the container. Denser than water and insoluble in water. Vapors are heavier than air. Produces toxic oxides of nitrogen during combustion.
Air & Water Reactions
Highly flammable. Insoluble in water.
Reactivity Profile
Organonitrates, such as Ethyl nitrate, range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation. Nitroalkanes are milder oxidizing agents, but still react violently with reducing agents at higher temperature and pressures. Nitroalkanes react with inorganic bases to form explosive salts. The presence of metal oxides increases the thermal sensitivity of nitroalkanes. Nitroalkanes with more than one nitro group are generally explosive.
Health Hazard
Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Hazard
Flammable, dangerous, fire and explosion
risk.
Description
Ethyl nitrate has formula C2H5NO3. It is used in organic synthesis and as an intermediate in the preparation of some drugs, dyes, and perfumes.
Ethyl nitrate is found in the atmosphere, where it can react with other gases to form smog. Originally thought to be a pollutant, formed mainly by the combustion of fossil fuels, recent analysis of ocean water samples reveal that in places where cool water rises from the deep, the water is saturated with alkyl nitrates, likely formed by natural processes.
Preparation
Ethyl nitrate has been prepared by bubbling gaseous nitryl fluoride through ethanol at ?10 °C . The reaction was subsequently studied in detail.
Production Methods
The alkyl nitrates are produced from the corresponding alcohols by esterification
with nitric acid in the presence of urea or urea nitrate.
Industrial uses
Ethyl nitrate is used in the synthesis of certain drugs, perfumes and dyes. It has
also found some use as a rocket fuel.
Metabolism
There is no information concerning the in vivo metabolism of ethyl nitrate, but it
seems likely that one route for biotransformation is hydrolysis to yield an alcohol
and nitrate. Such a pathway is common to other alkyl nitrates such as nitroglycerin
and amyl nitrate.
