General Description
Odorless white crystalline powder. Bitter taste.
Reactivity Profile
TRIPROLIDINE HYDROCHLORIDE MONOHYDRATE(6138-79-0) discolors on exposure to light.
Air & Water Reactions
Water soluble.
Health Hazard
SYMPTOMS: Symptoms of exposure to this compound may include depression to stimulation of the central nervous system, dry mouth, fixed dilated pupils, flushing, hallucinations, convulsions, urinary retention, cardiac arrhythmias and coma. Other symptoms may include excitability, drowsiness, nervousness, dizziness, high fever and sleeplessness. It can also cause sedation. It may also cause local anesthesia, dryness of the throat and nose and abdominal pain with vomiting or diarrhea.
Fire Hazard
Flash point data for this chemical are not available; however, TRIPROLIDINE HYDROCHLORIDE MONOHYDRATE is probably combustible.
Chemical Properties
TRIPROLIDINE HYDROCHLORIDE is a white, crystalline powder.
Uses
anticholinergic (opthalmic)
Uses
TRIPROLIDINE HYDROCHLORIDE is used as bulk pharmaceutical (antihistaminic). Product Data Sheet
Definition
TRIPROLIDINE HYDROCHLORIDE is a hydrate that is the monohydrate form of triprolidine hydrochloride. A sedating antihistamine, it is used for the symptomatic relief of uticaria, rhinitis, and various pruritic skin disorders.
Brand name
Actidil (GlaxoSmithKline);
Myidyl (USl).
Biological Activity
Potent H 1 receptor antagonist.
