Chemical Properties
yellow crystals or gold liquid
Uses
N-Nitrosomorpholine, a frequently used genotoxic model carcinogen. Toxicogenomic analysis of N-Nitrosomorpholine induced changes in rat liver.
Definition
ChEBI: A nitrosamine that is morpholine in which the hydrogen attached to the nitrogen is replaced by a nitroso group. A carcinogen and mutagen, it is found in snuff tobacco.
General Description
Yellow crystals. Golden liquid with many crystals at 68°F.
Air & Water Reactions
Water soluble.
Reactivity Profile
N-NITROSOMORPHOLINE is incompatible with strong oxidizing agents .
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition N-NITROSOMORPHOLINE emits toxic fumes of nitrogen oxides.
Fire Hazard
Flash point data for N-NITROSOMORPHOLINE are not available; however, N-NITROSOMORPHOLINE is probably combustible.
Biochem/physiol Actions
Tumor initiator in rodent liver, trachea, nasal cavity, esophagus, kidney, lung, and thyroid.
Carcinogenicity
N-Nitrosomorpholine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
