587-4-2

Papaverine is an analytical reference standard categorized as a muscle relaxant.^1,2,3 Papaverine has been found as an impurity in seized heroin .⁴ This product is intended for research and forensic applications.

Papaverine is a phosphodiesterase inhibitor.

1. Virag, R., Shoukry, K., Floresco, J., et al. Intracavernous self-injection of vasoactive drugs in the treatment of impotence: 8-Year experience with 615 cases J. Urol. 145(2),287-293(1991).
2. Vardiman, A.B., Kopitnik, T.A., Purdy, P.D., et al. Treatment of traumatic arterial vasospasm with intraarterial papaverine infusion AJNR Am. J. Neuroradiol. 16(2),319-321(1995).
3. Triner, L., Vulliemoz, Y., Schwartz, I., et al. Cyclic phosphodiesterase activity and the action of papaverine Biochem. Biophys. Res. Commun. 40(1),64-69(1970).
4. Cui, X., Lian, R., Chen, J., et al. Source identification of heroin by rapid detection of organic impurities using direct analysis in real time with high-resolution mass spectrometry and multivariate statistical analysis Microchem. J. 147,121-126(2019).