56189-68-5

Name	3,5-BIS(1,1-DIMETHYLETHYL)-4-HYDROXY-ALPHA,ALPHA-DIMETHYLBENZENEPROPANAL
CAS	56189-68-5
Molecular Formula	C19H30O2
MDL Number	MFCD04040029
Molecular Weight	290.44
MOL File	56189-68-5.mol

Synonyms

CGP 13501 3-(3',5'-DI-TERT-BUTYL-4'-HYDROXY)PHENYL-2,2-DIMETHYLPROPANAL 3,5-bis(1,1-Dimethylethyl)-4-hydroxy-α,α-dimethylbenzenepropanal Benzenepropanal, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-α,α-dimethyl- 3,5-BIS(1,1-DIMETHYLETHYL)-4-HYDROXY-ALPHA,ALPHA-DIMETHYLBENZENEPROPANAL

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Chemical Properties

storage temp.	Desiccate at +4°C
solubility	DMSO: 24 mg/mL, soluble
form	solid
color	white

Safety Data

WGK Germany

Hazard Information

Uses

CGP 13501 is a positive allosteric modulator at GABAB?receptors.

Definition

ChEBI: 3-(3,5-ditert-butyl-4-hydroxyphenyl)-2,2-dimethylpropanal is an alkylbenzene.

Biological Activity

Positive allosteric modulator of GABA B receptors, potentiating the effects of GABA at this receptor type.

References

[1]. urwyler s, mosbacher j, lingenhoehl k, et al. positive allosteric modulation of native and recombinant gamma-aminobutyric acid(b) receptors by 2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (cgp7930) and its aldehyde analog cgp13501. mol pharmacol, 2001, 60(5): 963-971.
[2]. rasheed n, ahmad a, al-sheeha m, et al. neuroprotective and anti-stress effect of a68930 in acute and chronic unpredictable stress model in rats. neurosci lett, 2011, 504(2): 151-155.

Supplier

3B Pharmachem (Wuhan) International Co.,Ltd.

Telephone821-50328103-801 18930552037

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList13285/0.htm

MedBioPharmaceutical Technology Inc

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Energy Chemical

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Websitehttps://www.univ-bio.com/

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Merck KGaA

Telephone(+86) 21 2033 8288

Websitehttp://www.sigmaaldrich.cn

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