Chemical Properties
White crystalline solid. Some formulations
are a dark brown liquid.
Uses
Plant growth regulator; herbicide.
Agricultural Uses
Herbicide; plant growth regulator: Not approved for use in EU countries
. Mefluidide
is used to control ornamental and non-ornamental woody
plants, ground cover, hedges, trees, turfgrass and broadleaf
weeds. Both the diethanolamine and potassium salts are
actively used in the U.S.
Trade name
EMmHgK®; MBR 12325®; MBR
12325®; METHAFLUORIDAMID®; S 15733®; VEL
3973®; VISTAR® Herbicide
Potential Exposure
Mefluidide is an anilide herbicide and
plant growth regulator used to control ornamental and nonornamental woody plants, ground cover, hedges, trees, turfgrass, and broadleaf weeds. Both the diethanolamine and
potassium salts are actively used in the United States Not
refistered for use in the EU.
First aid
If this chemical gets into the eyes, remove any
contact lenses at once and irrigate immediately for at least
15 minutes, occasionally lifting upper and lower lids. Seek
medical attention immediately. If this chemical contacts the
skin, remove contaminated clothing and wash immediately
with soap and water. Seek medical attention immediately.
If this chemical has been inhaled, remove from exposure,
begin rescue breathing (using universal precautions)
if breathing has stopped, and CPR if heart action
has stopped. Transfer promptly to a medical facility.
When this chemical has been swallowed, get medical
attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. Do not
induce vomiting when formulations containing petroleum
solvents are ingested
Shipping
UN3077 Environmentally hazardous substances,
solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required
Incompatibilities
May react with strong oxidizers such as
chlorates, peroxides, nitrates, etc
Waste Disposal
Dissolve or mix the material
with a combustible solvent and burn in a chemical
incinerator equipped with an afterburner and scrubber.
All federal, state, and local environmental regulations
must be observed.
Definition
ChEBI: Mefluidide is a sulfonamide.
Production Methods
The industrial synthesis of mefluidide begins with the derivatization of 2,4-dimethylaniline, which is acylated using acetic anhydride or acetyl chloride to form the acetanilide backbone. This intermediate then undergoes sulfonamidation with trifluoromethanesulfonyl chloride (triflic anhydride) under basic conditions to introduce the trifluoromethanesulfonamide group at the para position. The reaction is typically carried out in an organic solvent such as dichloromethane or acetonitrile, with a base like triethylamine to neutralise the by-product acid.
Mechanism of action
Growth inhibition, absorbed by foliage. Gibberellin biosynthesis inhibitor
Environmental Fate
Soil. Rapidly degrades in soil forming 5-amino-2,4-dimethyltrifluoromethane sulfone
anilide as the major metabolite (half-life <1 week) (Hartley and Kidd, 1987).
Pesticide Type
Herbicide; Plant Growth Regulator
