Delphinidin (chloride) is an anthocyanidin, a natural plant pigment which serves as the precursor of certain anthocyanins that provide the blue-
red colors of flowers, fruits, and red wine.
1 Delphinidin induces the release of nitric oxide by vascular endothelium, causing vasorelaxation.
2 It also inhibits signaling through epithelial growth factor receptors, suppressing the expression of estrogen receptor α and inducing both apoptosis and autophagy at a dose of 1-
40 μM.
3,4 Delphinidin also inhibits the histone acetyltransferase activities of p300/CBP (IC
50 = ~ 30 μM).
5