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Combustible. Central nervous system impairment, asthma, and hematologic effects.

(1,2,3-and 1,2,4-isomers): These materials are used as solvents and in dye and perfume manufacture. The 1,2,3-isomer is used as raw material in chemical synthesis and as an UV stabilizer. The 1,2,4-isomer is used as the raw material for trimellitic anhydride manufacture. These compounds are found in diesel engine exhaust fumes.

If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit.

UN3295 Hydrocarbons, liquid, n.o.s., Hazard Class: 3; Labels: 3-Flammable liquid. UN1993 Flammable liquids, n.o.s., Hazard Class: 3; Labels: 3-Flammable liquid, Technical Name Required. 1,3,5-Trimethylbenzene; UN2325, Hazard Class: 3; Labels: 3-Flammable liquid. 1,2,4-Trimethylbenzene:

Vapors may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.

colourless liquid

Trimethylbenzenes exists in three isomeric forms. All isomers are clear, colorless liquids with a distinctive, aromatic odor.

Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.

Clear, colorless, flammable liquid with an aromatic odor similar to propylbenzene, ethylbenzenes, or xylenes.

ChEBI: A trimethylbenzene carrying methyl groups at positions 1, 2 and 3. It has been found in Centaurium erythraea.

Journal of the American Chemical Society, 62, p. 2639, 1940 DOI: 10.1021/ja01867a017
Organic Syntheses, Coll. Vol. 4, p. 508, 1963

Detected in distilled water-soluble fractions of 87 octane gasoline (0.30 mg/L), 94 octane gasoline (0.81 mg/L), Gasohol (0.80 mg/L), No. 2 fuel oil (0.22 mg/L), diesel fuel (0.09 mg/L), and military jet fuel JP-4 (0.19 mg/L) (Potter, 1996).
Thomas and Delfino (1991) equilibrated contaminant-free groundwater collected from Gainesville, FL with individual fractions of three individual petroleum products at 24–25 °C for 24 h. The aqueous phase was analyzed for organic compounds via U.S. EPA approved test method 602. Average 1,2,3-trimethylbenzene concentrations detected in water-soluble fractions of unleaded gasoline, kerosene, and diesel fuel were 1.219, 0.405, and 0.118 mg/L, respectively.
When the authors analyzed the aqueous-phase via U.S. EPA approved test method 610, average 1,2,3-trimethylbenzene concentrations in water-soluble fractions of unleaded gasoline, kerosene, and diesel fuel were smaller, i.e., 742, 291, and 105 μg/L, respectively.

Photolytic. Glyoxal, methylglyoxal, and biacetyl were produced from the photooxidation of 1,2,3-trimethylbenzene by OH radicals in air at 25 °C (Tuazon et al., 1986a). The rate constant for the reaction of 1,2,3-trimethylbenzene and OH radicals at room temperature was 1.53 x 10^-11 cm³/molecule?sec (Hansen et al., 1975). A rate constant of 1.49 x 10^-8 L/molecule?sec was reported for the reaction of 1,2,3-trimethylbenzene with OH radicals in the gas phase (Darnall et al., 1976). Similarly, a room temperature rate constant of 3.16 x 10^-11 cm³/molecule?sec was reported for the vapor-phase reaction of 1,2,3-trimethylbenzene with OH radicals (Atkinson, 1985). At 25 °C, a rate constant of 2.69 x 10^-11 cm³/molecule?sec was reported for the same reaction (Ohta and Ohyama, 1985). 2,3-Butanedione was the only products identified from the OH radical-initiated reaction of 1,2,4-trimethylbenzene in the presence of nitrogen dioxide. The amount of 2,3- butanedione formed decreased with increased concentration of nitrogen dioxide (Bethel et al., 2000).
Chemical/Physical. 1,2,3-Trimethylbenzene will not hydrolyze because it does not contain a hydrolyzable group (Kollig, 1993).