General Description
White crystalline solid. Corrosive eye irritant. Used as an herbicide.
Reactivity Profile
A triazine.
Air & Water Reactions
Water soluble. Rapidly decomposed in solution by strong acids and bases.
Description
Hexazinone is a white crystalline solid that ispractically odorless. Molecular weight = 252.36; Boilingpoint = decomposes; FreezingMelting point= 115-117℃; .Vapor pressure= 3.0X 10厂' mmHg. Soluble in water.
Definition
ChEBI: Hexazinone is a member of 1,3,5-triazines.
Production Methods
Hexazinone is a postemergence contact herbicide effective
against many annual and biennial weeds and, except for
Johnson grass, most perennial weeds. Human contact is
likely at the use stage, and dermal contact and inhalation
are of most concern.
Potential Exposure
Those involved in the manufacture,formulation, and application of this contact and residualherbicide. It is a broad spectrum herbicide used in industrialand government right-of-way weed control for pipelines,drainage ditches, etc.
First aid
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek med-ical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescuebreathing (using universal precautions, includ-ing resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medi-cal attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.
Carcinogenicity
No carcinogenicity was detected
among pups of rats fed up to 5000 ppm for 2 years.
Similarly, no increase in tumors was produced by feeding up
to 10,000 ppm hexazinone to mice.
Environmental Fate
Soil/Plant. Biodegrades in soil and natural waters releasing carbon dioxide. The reported half-life in soil is 1 to 6 months (Hartley and Kidd, 1987). Rhodes (1980a) found that the persistence of hexazinone varied from 4 weeks in a Delaware sandy loam to 24 weeks in a Mississippi silt loam.
Hexazinone is subject to microbial degradation (Rhodes, 1980a; Feng, 1987). Metabolites identified in soils, alfalfa and/or sugarcane include 3-(4-hydroxycyclohexyl)-6(dimethylamino)-1-methyl-1,3,5-triazine-2,4(1H,3H)-dione, 3-cyclohexyl-6-(methylamino)-1
Feng (1987) monitored the persistence and degradation of hexazinone in a silt loam soil 104 days after treatment of the herbicide. After 104 days, 66% of the hexazinone degraded via hydroxylation to form the major metabolite 3-(4-hydroxycyclohexyl)-6(dime
No traces of hexazinone or its metabolites were detected on treated blueberries (Jenson and Kimball, 1985).
Photolytic. Photodegradation products identified in aqueous hexazinone solutions following exposure to UV light (λ = 300–400 nm) were 3-(4-hydroxycyclohexyl)-6-(dimethylamino)-1-methyl-1,3,5-triazine-2,4(1H,3H)-dione, 3-cyclohexyl-6-(methylamino)
Metabolic pathway
In clay and sand soils, hexazinone is metabolized by
hydroxylation at the 4-position of the cyclohexane ring
and mono-N-demethylation to give [3-(4-
hydroxycyclohexyl)-6-(dimethylamino)-1-methyl-1,3,5-
triazine-2,4-(1H,3H )-dione], and [3-cyclohexyl-6-
(methylamino)-1-methyl-1,3,5-triazine-2,4-(1H,3H )-
dione, respectively. N-Demethylated metabolite is
found in a comparatively higher percentage than the
hydroxylated metabolite in both clay and sand soils.
storage
Color Code- -Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool, well-venti lated area above 32℃.
Shipping
Hexazinone is classified as Triazine pesticides,solid, toxic n.o.s. This compound requires a shipping labelof“POISONOUS/TOXIC MATERIALS.”It falls in HazardClass 6.1 and Packing Group II.
;