General Description
Colorless to light yellow liquid. Floats on water. Freezing point is 21°F.
Reactivity Profile
Ketones, such as DI-N-BUTYL KETONE(502-56-7), are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4. May attack some forms of plastics [USCG, 1999].
Air & Water Reactions
Highly flammable.
Health Hazard
Inhalation causes irritation of nose and throat. Ingestion causes irritation of mouth and stomach. Contact with eyes or skin causes irritation.
Chemical Properties
5-Nonanone is a stable and colorless-to-light yellow
liquid.
No human odor threshold was identified for 5-nonanone.
However, Laska et al. demonstrated using a conditioning
paradigm that the olfactory threshold of squirrel monkeys
and pigtail caques for 5-nonanone is below 1 ppb .
Chemical Properties
CLEAR COLOURLESS TO SLIGHTLY YELLOW LIQUID
Uses
5-Nonanone is used in preparation of 6-(1,2,4-oxadiazol-5-yl)chroman-4-one derivatives as S1P1 receptor modulators and methods for preparing them.
Synthesis Reference(s)
Journal of the American Chemical Society, 89, p. 2738, 1967
DOI: 10.1021/ja00987a043The Journal of Organic Chemistry, 52, p. 5570, 1987
DOI: 10.1021/jo00234a012Tetrahedron Letters, 7, p. 6145, 1966
Chemical Reactivity
Reactivity with Water No reaction; Reactivity with Common Materials: May attack some forms of plastics; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
Biochem/physiol Actions
5-Nonanone induces clinical neuropathy in rats.
