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496864-14-3
496864-14-3
Name
Aloisine B
CAS
496864-14-3
Molecular Formula
C15H14ClN3
Molecular Weight
271.74
MOL File
496864-14-3.mol
Synonyms
Aloisine B
5H-Pyrrolo[2,3-b]pyrazine, 6-(4-chlorophenyl)-7-(1-methylethyl)-
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Description
Aloisine B is a potent and selective CDK and GSK-3 inhibitor. Highest affinity targets: Glycogen Synthase Kinase-3, Beta (Rattus norvegicus (rat)) (IC50 750.0 nM). Other measured targets: Cyclin-Dependent Kinase 1 (CDK1) (IC50 850.0 nM); Cyclin-Dependent Kinase 5 (CDK5) (IC50 13000.0 nM). Aloisine inhibits cell proliferation by arresting cells in both G1 and G2.
Supplier
Shanghai Yifei Biotechnology Co. , Ltd.
Telephone
021-65675885 18964387627
Website
http://www.efebio.com
TargetMol Chemicals Inc.
Telephone
15002134094
Website
https://www.targetmol.cn/
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