4150-30-5

5-Androstenetriol is a systemic radiation protector that can boost the host's immunity, leading to increased resistance to infections. 5-Androstenetriol can raise levels of IL-2, IL-3, and IFN, while countering the immunosuppressive effects of Hydrocortisone (HY-N0583)[1][2].

ChEBI: 5-Androstenetriol is a 3-hydroxy steroid. It has a role as an androgen.

IL-2; IL-3

[1] R M Loria, et al. Androstenetriol and androstenediol. Protection against lethal radiation and restoration of immunity after radiation injury. Ann N Y Acad Sci. 2000:917:860-7. DOI:10.1111/j.1749-6632.2000.tb05452.x
[2] Mark H Whitnall, et al. Molecular specificity of 5-androstenediol as a systemic radioprotectant in mice. Immunopharmacol Immunotoxicol. 2005;27(1):15-32. DOI:10.1081/iph-51289