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404950-80-7

Supplier Related Products Identification Chemical Properties Hazard Information Safety Data

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Identification

Name
(E)-N-HYDROXY-3-(4-{[2-(2-METHYL-1H-INDOL-3-YL)-ETHYLAMINO]-METHYL}-PHENYL)-ACRYLAMIDE
CAS
404950-80-7
Synonyms
LBH-589
NVP-LBH589
PANOBINOSTAT
LBH-589/Panobinostat
Panobinostat (LBH589)
panobinostat (HDAC inhibitor)
N-Hydroxy-3-[4-[2-(2-methyl-1H-indol-3-yl)ethylaminomethyl]phenyl]-2(E)-propenamide
(E)-N-HYDROXY-3-(4-{[2-(2-METHYL-1H-INDOL-3-YL)-ETHYLAMINO]-METHYL}-PHENYL)-ACRYLAMIDE
2-Propenamide, N-hydroxy-3-(4-(((2-(2-methyl-1H-indol-3-yl)ethyl)amino)methyl)phenyl)-, (2E)-
Panobinostat N-Hydroxy-3-[4-[2-(2-methyl-1H-indol-3-yl)ethylaminomethyl]phenyl]-2(E)-propenamide
N-Hydroxy-3-[4-[2-(2-methyl-1H-indol-3-yl)ethylaminomethyl]phenyl]-2(E)-propenamide Panobinostat (LBH589)
Molecular Formula
C21H23N3O2
MDL Number
MFCD09833242
MOL File
404950-80-7.mol
Molecular Weight
349.426

Chemical Properties

mp 
114-117?C
storage temp. 
-20°C Freezer, Under Inert Atmosphere

Hazard Information

Chemical Properties
Yellow Solid
Usage
The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph-acute lymphoblastic leukemia cells.
Usage
The novel labelled histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph-acute lymphoblastic leukemia cells.

Safety Data

HS Code 
29339900
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