STAT3-IN-24, cell-permeable (PpYLKTK-mts) is a STAT3 peptide inhibitor. STAT3-IN-24, cell-permeable inhibits recruitment of STAT3 to Jak2 and phosphorylation of Y705, thus preventing the dimerization and the nuclear translocation of STAT3[1].
References
[1] Buettner C, et al. Critical role of STAT3 in leptin's metabolic actions. Cell Metab. 2006 Jul;4(1):49-60. DOI:10.1016/j.cmet.2006.04.014
