39837-08-6

N-Butyryl-DL-homocysteine thiolactone is an N-acyl homoserine lactone (AHL) analogue. AHLs are potent inhibitors of biofilm formation and virulence factors, and has been used for degrading microbial communities, reducing bacterial pathogenicity[1][2].

[1] Khalilzadeh P, et al. Growth inhibition of adherent Pseudomonas aeruginosa by an N-butanoyl-L-homoserine lactone analog. Can J Microbiol. 2010 Apr;56(4):317-25. DOI:10.1139/w10-013
[2] Iyer R, et al. Synthetic analogs of bacterial quorum sensors: US, US20110053890[P]. 2011-03-03.