SLV-317 is an antagonist of the neurokinin-1 receptor with oral activity. SLV-317 can effective antagonist of substance P-induced effects[1].
References
[1] Christiane Hesse, et al. Kinetics and dynamics of the peripheral neurokinin-1 receptor antagonist SLV317 in healthy individuals. Br J Clin Pharmacol. 2006 Apr;61(4):414-9. DOI:10.1111/j.1365-2125.2006.02590.x
