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Sorbitan sesquioleate is a mixture of mono and diesters of oleic acid and extol anhydrides derived from sorbitol. It is used as a surfactant and an emulsifier in cosmetics. It acts sometimes as a contact allergen, particularly in leg ulcer patients. It is also responsible for false-positive patch test reactions to haptens, with which some allergen providers emulgated, such as parabens mix, fragrance mix, Amerchol L101, and ethylene-urea /melamine formaldehyde.