Uses
Chlorophacinone (CPN) is an anticoagulant rodenticide widely used to control rodent infestations.
Uses
Anticoagulant rodenticide.
General Description
Crystals. Commercially available as oil concentrate and as dust concentrate. Used as an anticoagulant rodenticide. Chronic acting, multiple dose rodenticide.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Fire may produce irritating or poisonous gases.
Health Hazard
Chlorphacinon is highly toxic orally and by skin absorption. The probable oral lethal dose for humans is less than 5 mg/kg to 50 mg/kg, or between a taste (less than 7 drops) and 1 teaspoonful for a 150 lb. (70 kg) person.
Fire Hazard
(Non-Specific -- Coumarin Derivative Pesticide, Solid, n.o.s.) Fire may produce irriating or poisonous gases. Runoff from fire control water may give off poisonous gases. Runoff from fire control or dilution water may cause pollution. When heated Chlorphacinon emits toxic fumes of chlorides.
Potential Exposure
Agricultural Chemical. This material
is an anticoagulant rodenticide. A potential danger to those
involved in its manufacture, formulation, and application
are at risk.
First aid
If this chemical gets into the eyes, remove any
contact lenses at once and irrigate immediately for at least
15 minutes, occasionally lifting upper and lower lids. Seek
medical attention immediately. If this chemical contacts the
skin, remove contaminated clothing and wash immediately
with soap and water. Seek medical attention immediately.
If this chemical has been inhaled, remove from exposure,
begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and
CPR if heart action has stopped. Transfer promptly to a
medical facility. When this chemical has been swallowed,
get medical attention. Give large quantities of water and
induce vomiting. Do not make an unconscious person
vomit.
Shipping
UN3027 Coumarin derivative pesticides, solid,
toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
Description
Chlorophacinone is produced by condensation of 1-
phenyl-1-(4-chlorophenyl) acetone with dimethyl phthalate
in the presence of sodium methoxide (31).
This compound was introduced in 1961 and is now
widely used in Europe, the United States, and elsewhere.
It is used in baits against norway rats at a concentration
of 0.005–0.01%. Bait containing 0.025% chlorophacinone
gave a complete kill of house mice after a 7-d feeding
period but, in other tests, survivors were recorded following
10 and 21 days of feeding (5). Chlorophacinone acts as
an uncoupler of oxidative phosphorylation as well as an
anticoagulant (32), which is unusual among this group of
compounds.
Chemical Properties
Chlorophacinone is a highly toxic crystalline
solid.
Waste Disposal
Incineration at high temperature with effluent gas scrubbing.
Definition
ChEBI: Chlorophacinone is a diarylmethane and a beta-triketone.
Agricultural Uses
Rodenticide: This material is an anticoagulant rodenticide used around livestock and also on crops such as artichokes. Some brands are labeled for use indoors and outdoors for the control of mice, rats, moles, muskrats, voles and vampire
bats. Not approved for use in EU countries. Registered for use in the U.S. There are 24 global suppliers.
Trade name
AFNOR®; CAID®; DELTA®; DRAT RAT BAIT®; ENDORATS®; LIPHADIONE®; LM 91®; MICROZUL®; MURIOL®; PARTOX®[C]; QUICK®; RAMUCIDE®; RANAC®; RATOMET®; RAVIAC®; ROZOL®[C]; TOPITOX®
storage
Color Code—Green: General storage may be used.Prior to working with this chemical you should be trainedon its proper handling and storage. Store in tightly closedcontainers in a cool, well-ventilated area.