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345-78-8

Name (1S,2S)-(+)-Pseudoephedrine hydrochloride
CAS 345-78-8
EINECS(EC#) 206-462-1
Molecular Formula C10H16ClNO
MDL Number MFCD00058088
Molecular Weight 201.69
MOL File 345-78-8.mol

Chemical Properties

Appearance white powder
Melting point  185-188 °C(lit.)
alpha  61 º (c=5, H2O,2dm tube)
storage temp.  Refrigerator (+4°C)
solubility  Freely soluble in water and in ethanol (96 per cent), sparingly soluble in methylene chloride.
form  neat
pka 9.22(at 25℃)
Merck  13,8007
BRN  3915112
Contact allergens
This sympathomimetic a-adrenergic agonist is found in plants of the genus Ephedra (Ephedraceae) and is systemically used as a nasal decongestant. It can induce drug skin reactions such as acute generalized exanthematic pustulosis or generalized eczema.
CAS DataBase Reference 345-78-8(CAS DataBase Reference)
EPA Substance Registry System 345-78-8(EPA Substance)

Safety Data

Hazard Codes  Xn
Risk Statements 
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Statements 
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S24/25:Avoid contact with skin and eyes .
RIDADR  1544
WGK Germany  3
RTECS  UL5950000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29394200
Toxicity
LD50 i.p. in mice: 1.0 mmole/kg (Fairchild, Alles)

Hazard Information

Material Safety Data Sheet(MSDS)

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