Ginsenoside Ro is a non-steroid glycoside that has been found in plants of the genus
Panax and has anti-inflammatory, antithrombotic, and antiviral biological activities.
1,2,3,4,5,6 It inhibits LPS-induced release of reactive oxygen species (ROS) and nitric oxide (NO) as well as inducible nitric oxide synthase (iNOS) and COX-2 protein expression in RAW 264.7 murine macrophages when used at a concentration of 200 μM.
2 Ginsenoside Ro dose-dependently inhibits human platelet aggregation induced by thrombin (Item No.
13188)
in vitro and thrombin-induced disseminated intravascular coagulation (DIC) in rats when administered at a dose of 100 mg/kg.
3,4 It increases the 20-day survival of Sendai virus-infected mice when administered at a dose of 1 mg per day for three days prior to infection.
5 Topical administration of ginsenoside Ro (0.2 mg per animal) also stimulates hair regrowth after shaving in a mouse model of slowed hair regrowth.
6