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UA62784 is a centromere protein E (CENP-E) inhibitor.

Studies have also reported th at UA62784 associates with tubulin at or near the colchicine-binding sites in cells and functions as a cytotoxicmicrotubule inhibitor.''UA62784 is a specific inhibitor of centromere protein E (CENPE) kinesin-like protein; mitotic inhibitor. CENP-E is a kinesin-like motor protein th at localizes to the kinetochore during mitosis and is essential for bipolar spindle formation. UA62784 is a novel specific inhibitor of CENP-Ewhich likely binds within the motor domain of CENP-E. UA62784 causes reversible cell cycle arrest in mitosis before metaphasewhich leads to apoptosis. The compound is not interacting with microtubules directly.