311-45-5

Name	PARAOXON
CAS	311-45-5
EINECS(EC#)	206-221-0
Molecular Formula	C10H14NO6P
MDL Number	MFCD00007316
Molecular Weight	275.2
MOL File	311-45-5.mol

Chemical Properties

Appearance	Paraoxon is an odorless, reddish-yellow oil. Fruity odor.
Melting point	300°C
Boiling point	169-170°C
density	1.274 g/mL at 25 °C(lit.)
refractive index	n20/D 1.51(lit.)
storage temp.	2-8°C
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form	oil
color	yellow
Odor	slt odor
Water Solubility	3.627g/L(20 ºC)
Merck	13,7102
BRN	1915526
Stability:	Moisture Sensitive
CAS DataBase Reference	311-45-5
EPA Substance Registry System	Paraoxon (311-45-5)

Safety Data

Hazard Codes	T+,N
Risk Statements	26/27/28-50 less more
Safety Statements	36/37/39-45-61 less more
RIDADR	UN 2810 6.1/PG 1
WGK Germany	3
RTECS	TC2275000
HazardClass	6.1(a)
PackingGroup	I
Hazardous Substances Data	311-45-5(Hazardous Substances Data)
Toxicity	LD50 orally in rats: 1.8 mg/kg (Pickering, Malone) less more

Raw materials And Preparation Products

Hazard Information

Chemical Properties

Oily Liquid

Uses

A cholinesterase inhibitor

Definition

ChEBI: An aryl dialkyl phosphate where both the alkyl groups are ethyl and the aryl group is 4-nitrophenyl.

Uses

Insecticide.

General Description

Reddish-yellow oily liquid with a faint fruity odor.

Reactivity Profile

Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Fire Hazard

Flash point data for PARAOXON are not available; however, PARAOXON is probably combustible.

Potential Exposure

An organophosphate insecticide. Has been used as a medication.

First aid

If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Speed in removing material from skin is of extreme importance. Shampoo hair promptly if contaminated. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit.

Shipping

UN3018 Organophosphorus pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Incompatibilities

Keep away from alkaline materials and strong oxidizers. Contact with oxidizers can cause the release of toxic oxides of phosphorus. May react violently with antimony(V) pentafluoride. Incompatible with lead diacetate, magnesium, silver nitrate. In the presence of strong reducing agents such as hydrides, organophosphates form highly toxic and flammable phosphine gas.

Waste Disposal

In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.

Synthesis Reference(s)

Tetrahedron Letters, 31, p. 3359, 1990 DOI: 10.1016/S0040-4039(00)89065-6

Biochem/physiol Actions

Potent irreversible acetylcholinesterase inhibitor

Safety Profile

A deadly poison by ingestion,intraperitoneal, intravenous, subcutaneous, intramuscular,and parenteral routes. Mutation data reported. Humansystemic effects: coma, convulsions, miosis. Acholinesterase inhibitor. An insecticide. When heated todecompos

Spectrum Detail

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