CDK4/6-IN-19 (Compound II-7) is a CDK4/CDK6 inhibitor with IC50 values ??of 0.2, 5.0 nM, respectively. CDK4/6-IN-19 also inhibits cell proliferation and can be used in cancer research[1].
IC 50
CDK4: 0.2 nM (IC50); CDK6: 5.0 nM (IC50)
References
[1] HU, Pu, et al. 2-aminopyrimidine compound, and use and pharmaceutical composition thereof.WO2024066986A1.
