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CAS DataBase List
3032733-17-5
3032733-17-5
Name
LRRK2-IN-13
CAS
3032733-17-5
Molecular Formula
C19H19ClN8O2
Molecular Weight
426.86
MOL File
3032733-17-5.mol
Synonyms
LRRK2-IN-13
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Chemical Properties
Boiling point
675.6±65.0 °C(predicted)
density
1.60±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka
2.05±0.20(predicted)
Hazard Information
Uses
LRRK2-IN-13 (Compound 13) is an inhibitor of LRRK2 (IC50=0.57 nM). LRRK2-IN-13 has brain penetrating properties[1].
References
[1] Jensen, T, et al. Preparation of substituted 2,4,12,13-tetrahydro-11H-5,7-(azenometheno)dipyrazolo[3,4-b:5',1'-g][1]oxa[4,6,8]triazacycloundecine derivatives as leucine-rich repeat kinase 2 (LRKK2) inhibitors. World Intellectual Property Organization,?WO2024056775?A1 2024-03-21
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TargetMol Chemicals Inc.
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15002134094
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https://www.targetmol.cn/
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