303156-68-5

(–)-Rasfonin is a fungal metabolite that has been found in T. terrophilus.¹ It inhibits proliferation of mouse splenocytes induced by concanavalin A and LPS (IC₅₀s = 0.7 and 0.5 μg/ml, respectively).

1. Fujimoto, H., Okamoto, Y., Sone, E., et al. Eleven new 2-pyrones from a fungi imperfecti, Trichurus terrophilus, found in a screening study guided by immunomodulatory activity Chem. Pharm. Bull. (Tokyo) 53(8),923-929(2005).