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CAS DataBase List
3030576-47-4
3030576-47-4
Name
NA
CAS
3030576-47-4
Molecular Formula
C33H39ClF2N6O3
Molecular Weight
641.15
MOL File
3030576-47-4.mol
Synonyms
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Chemical Properties
density
1.42±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
Hazard Information
Uses
KRAS inhibitor-24 (compound 115c) is a pyridopyrimidine KRAS inhibitor, with an IC50 of < 100 nM for KRas G12V, KRas WT and KRas G12R[1].
IC 50
KRas G12V: < 100 nM (IC
50
); K-Ras WT: < 100 nM (IC
50
); KRas G12R: < 100 nM (IC
50
)
References
[1] James Paul LAJINESS, et al. Pyridopyrimidine kras inhibitors. Patent WO 2024/040131 A1.
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TargetMol Chemicals Inc.
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15002134094
Website
https://www.targetmol.cn/
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