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5α-Dihydrodeoxycorticosterone could promote prostate cancer cell proliferation through androgen receptor (AR) activation.

ChEBI: 5alpha-dihydrodeoxycorticosterone is a 3-oxo-5alpha-steroid formed from 11-deoxycorticosterone by reduction across the C4-C5 double bond. It has a role as a progesterone receptor agonist, a GABA modulator and an anticonvulsant. It is a 21-hydroxy steroid, a 3-oxo-5alpha-steroid, a 20-oxo steroid, a primary alpha-hydroxy ketone and a mineralocorticoid. It is functionally related to an 11-deoxycorticosterone. It derives from a hydride of a 5alpha-pregnane.