ChemicalBook CAS DataBase List 2639365-69-6

2639365-69-6

Name	(S)-4-((4-((2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamoyl)quinolin-8-yl)amino)-4-oxobutanoic acid
CAS	2639365-69-6
Molecular Formula	C21H19F2N5O5
Molecular Weight	459.4
MOL File	2639365-69-6.mol

Chemical Properties

Boiling point	913.5±65.0 °C(Predicted)
density	1.50±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
form	Solid
pka	4.52±0.10(Predicted)
color	White to light yellow

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Animal Model:	Xenograft model of humanized FAP renal cancer (SK-RC-52.hFAP) in nude mice^[1]
Dosage:	50, 125, 250, 500 nmol/kg, and 1 μmol/kg (in the form of 177Lu-OncoFAP-DOTAGA)
Administration:	Intravenous injection (i.v.), single dose
Result:	Reached 32% of the injected dose per gram of tumor tissue (ID/g) within 10 minutes and maintained above 20% ID/g for 6 hours.

2639365-69-6

Chemical Properties

Hazard Information

Uses

Biological Activity

in vivo

References

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