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26309-95-5

Name (pivaloyloxy)methyl [2S-[2alpha,5alpha,6beta(S*)]]-6-(2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate monohydrochloride
CAS 26309-95-5
EINECS(EC#) 247-604-2
Molecular Formula C22H30ClN3O6S
Molecular Weight 500.008
MOL File 26309-95-5.mol
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Chemical Properties

Melting point  155-156° (decomp)
alpha  D20 +196° (c = 1 in water)
pka pKa ~7.0(at 25℃)
Contact allergens
Pivampicillin is a prodrug of ampicillin. It caused sensitization in 56 workers at a penicillin factory. Pivampicillin and pivmecillinam were responsible for contact dermatitis in pharmaceutical production workers. Ampicillin, mecillinam or amdinocillin, penicillin V and penicillin G were also implicated in cross-reactions.

Safety Data

Toxicity
LD50 in mice, rats (g/kg): 3.34, 5.00 orally; 3.60, 4.50 s.c. (von Daehne)

Hazard Information

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