247037-81-6

Name	methyl (R)-4-(2-chloro-4-fluorophenyl)-6-methyl-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate
CAS	247037-81-6
Molecular Formula	C17H15ClFN3O2S
Molecular Weight	379.84
MOL File	247037-81-6.mol

Synonyms

BAY395493 BAY-395493 BAY 395493 BAY39-5493 BAY 39-5493 BAY-39-5493 BAY395493,BAY39 5493 Ethyl (R)-4-(2-Chloro-4-fluorophenyl)-6-methyl-2-(2-thiazolyl)-1,4-dihydropyrimidine-5-carboxylate (R)-ethyl 4-(2-chloro-4-fluorophenyl)-6-methyl-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate methyl (R)-4-(2-chloro-4-fluorophenyl)-6-methyl-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate 5-Pyrimidinecarboxylic acid, 4-(2-chloro-4-fluorophenyl)-1,4-dihydro-6-methyl-2-(2-thiazolyl)-, ethyl ester, (4R)-

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Hazard Information

Uses

BAY39-5493 is a non-nucleoside inhibitor that inhibits HBV replication. BAY39-5493 inhibits viral DNA replication by preventing the formation of viral core particles (nucleocapsids). The IC50 value of BAY39-5493 against HBV in stably transfected HepG2.2.15 cells is 0.03 μM[1].

References

[1] Deres K, et al. Inhibition of hepatitis B virus replication by drug-induced depletion of nucleocapsids[J]. Science, 2003, 299(5608): 893-896. DOI:10.1126/science.1077215

Supplier

Chengdu Focus Pharmaceutical Technology Co., Ltd.

Telephone028-64950838 17340131597

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList30205/0_EN.htm

TCI (Shanghai) Chemical Trading Co., Ltd.

Telephone021-61109150

Websitehttps://www.tcisct.com

TargetMol Chemicals Inc.

Telephone 4008200310

Websitehttps://www.targetmol.cn/

Shanghai Haohong Scientific Co., Ltd.

Telephone400-8210725 4008210725

Websitehttps://www.leyan.com/

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