2419107-97-2

NF-κB/PON1-IN-1 (Compound 16) is a NF-κB/PON1 pathway inhibitor. NF-κB/PON1-IN-1 has antioxidant (IC50 = 45.76 μM) and hepatoprotective activities[1].

[1] Soliman AM, et al. Antioxidant activity of novel quinazolinones bearing sulfonamide: Potential radiomodulatory effects on liver tissues via NF-κB/ PON1 pathway. Eur J Med Chem. 2020 Jul 1;197:112333. DOI:10.1016/j.ejmech.2020.112333