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Dihydropteroate synthase-IN-1 (compound 5g) is a potent dihydropteroate synthase (DHPS) inhibitor. Dihydropteroate synthase-IN-1 shows antimicrobial activities and antifungal activity. Dihydropteroate synthase-IN-1 inhibits cytochromes P450. Dihydropteroate synthase-IN-1 can bu used as diagnostic radio imaging material[1].

[1] Nasr T, et al. New acrylamide-sulfisoxazole conjugates as dihydropteroate synthase inhibitors. Bioorg Med Chem. 2020 May 1;28(9):115444. DOI:10.1016/j.bmc.2020.115444