2243566-45-0

m-PEG3-triethoxysilane is a PEG linker containing a triethoxysilane moiety. Triethoxysilane is commonly used for surface modifications. The hydrophilic PEG linkers increase the water solubility of a compound in aqueous media. The water solubility properties of the PEG linkers are enhanced with longer PEG chains.

m-PEG3-amido-C3-triethoxysilane is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

PEGs

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005