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AS2541019 is a selective Phosphatidylinositol-3-kinase p110δ (PI3Kδ) inhibitor.

AS2541019 is a PI3Kδ (p110δ) inhibitor. AS2541019 inhibits B cell activation and proliferation, and suppresses xenograft antibody production[1].

p110δ

[1] Marui T, et al. Effects of AS2541019, a novel selective PI3Kδ inhibitor, on antibody production and hamster to rat xenotransplantation. Eur J Pharmacol. 2018 May 5;826:179-186. DOI:10.1016/j.ejphar.2018.02.046