1912399-75-7
| Name | BT11 |
| CAS | 1912399-75-7 |
| Molecular Formula | C30H24N8O2 |
| Molecular Weight | 528.56 |
| MOL File | 1912399-75-7.mol |
Synonyms
BT11
BT11;BT 11
BT-11, >98%
Methanone, 1,1'-(1,4-piperazinediyl)bis[1-[6-(1H-benzimidazol-2-yl)-2-pyridinyl]-
[4-[6-(1~{H}-benzimidazol-2-yl)pyridine-2-carbonyl]piperazin-1-yl]-[6-(1~{H}-benzimidazol-2-yl)pyridin-2-yl]methanone
Hazard Information
Biological Activity
BT11 is an orally active compound that binds to lanthionine synthetase C-like 2 (LANCL2) with a Kd value of 7.7 μM and can be used for the treatment of inflammatory bowel disease.
in vivo
Oral administration of 8 mg/kg/day BT-11 to mice attenuates colitis. In the drug safety testing experiment in rats, oral high concentrations of BT-11 have good safety (detection concentration up to 1000 mg/kg/day).
target
| Target | Value |
| LANCL2 () |