SJ26 is a Wnt1 inhibitor with anticancer activity. SJ26 inhibits the expression of Wnt1 and Wnt1-mediated downstream signaling pathways in a G-quadruplex structure-dependent manner to suppress the migration activity of cancer cells[1].
References
[1] Liencheng Chang, et al. "Identification of a new class of WNT1 inhibitor: Cancer cells migration, G-quadruplex stabilization and target validation." Oncotarget 7.42 (2016): 67986. DOI:10.18632/oncotarget.6622
