1780390-76-2

Name	6-Quinazolinecarbonitrile, 4-[(2-phenylethyl)amino]-, hydrochloride (1:1)
CAS	1780390-76-2
Molecular Formula	C17H15ClN4
Molecular Weight	310.79
MOL File	1780390-76-2.mol

Synonyms

6-Quinazolinecarbonitrile, 4-[(2-phenylethyl)amino]-, hydrochloride (1:1)

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Chemical Properties

solubility

Soluble to 100 mM in DMSO

Hazard Information

Uses

Senexin A is a useful intermediate.

in vivo

Senexin A hydrochloride (5 times daily) completely reverses the tumor-promoting effects of chemotherapy. Senexin A hydrochloride had no significant toxicity to body weight, organ weights, or blood cell counts in C57BL/6 mice during treatment. Senexin A hydrochloride treatment significantly improves A549/MEF tumor response to Doxorubicin (HY-15142A)^[1].

IC 50

CDK8: 280 nM (IC₅₀); CDK8: 0.83 μM (Kd); CDK19: 0.31 μM (Kd)

storage

Store at +4°C

Supplier

Jinan Jiuli Biotechnology Co. , Ltd.

Telephone 15865264761

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList89365/0_EN.htm

Nantong QuanYi Biotechnology Co., Ltd

Telephone0513-66337626 18051384581

Websitehttps://www.chemhifuture.com/

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

R&D Systems, Inc

Telephone18003437475

Websitehttp://www.rndsystems.com

Biosynth Biological Technology (Suzhou) Co Ltd

Telephone 51288865780

Websitehttp://www.biosynth.com

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