169736-88-3

PHYLPA-8 is an inhibitor for DNA polymerase-α, which exhibits weak inhibitory activity for the stereochemistry of the fatty acid moiety and the cyclic phosphate[1].

[1] Murakami-Murofushi K, et al., Selective inhibition of DNA polymerase-alpha family with chemically synthesized derivatives of PHYLPA, a unique Physarum lysophosphatidic acid. Biochim Biophys Acta. 1995 Aug 24;1258(1):57-60. DOI:10.1016/0005-2760(95)00097-v