1560968-27-5

MIV-6 is an inhibitor of the menin-mixed lineage leukemia (MLL) interaction that closely mimics a natural protein-protein interaction.

MIV-6 is a small molecule inhibitor that inhibits menin-mixed lineage leukemia (MLL) interaction and exhibits strong selective activity in MLL leukemia cells with IC50 = 56 nM.

[1] High-affinity small-molecule inhibitors of the menin-mixed lineage leukemia (MLL) interaction closely mimic a natural protein-protein interaction