152323-73-4

GR 83895 is a prototype fibrinogen receptor antagonist.

GR83895 is a RGD based peptide, and inhibits ADP-induced platelet aggregation of human gel-filtered platelets (IC50= 0.9 μM)[1].

[1] Foster MR, et al. Improved potency and specificity of Arg-Gly-Asp (RGD) containing peptides as fibrinogen receptor blocking drugs. Thromb Res. 1993 Nov 1;72(3):231-45. DOI:10.1016/0049-3848(93)90190-y