Identification Chemical Properties Safety Data Hazard Information Supplier Related Products

143-50-0

Name KEPONE (TM)
CAS 143-50-0
EINECS(EC#) 205-601-3
Molecular Formula C10Cl10O
MDL Number MFCD00213544
Molecular Weight 490.64
MOL File 143-50-0.mol

Chemical Properties

Description
Chemically, kepone is a chlorinated polycyclic insecticide and fungicide. Chlordecone was used as an insecticide for leaf-eating insects, ants, and cockroaches; as a larvicide for flies; and for control of insects that attack structures. Chlordecone was also used on bananas, nonbearing citrus trees, tobacco, ornamental shrubs, lawns, turf, and flowers. The dry powder is readily absorbed through the skin and respiratory tract. Occupational workers handling kepone without appropriate workplace safety dress and PPE suffered chemical poisoning. The symptoms included, tremors, jerky eye movements, memory loss, headaches, slurred speech, unsteadiness, lack of coordination, loss of weight, rash, enlarged liver, decreased libido, sterility, chest pain, and arthralgia (sharp pain, extending along a nerve or group of nerves, experienced in a joint and/or joints). Chlordecone was first introduced as a pesticide in 1958 and was used until 1978, when its use in the United States was discontinued (NCI 1976, IARC 1979, HSDB 2009).
Appearance Kepone is a tan to white, odorless crystalline solid.
Melting point  350℃ (DEC.)
Boiling point  450.5±45.0 °C(Predicted)
density  2.27
vapor pressure  2.25 x 10-7 mmHg at 25 °C (Kilzer et al., 1979)
Fp  >100 °C
storage temp.  0-6°C
solubility  Soluble in acetic acid, alcohols, and ketones (Windholz et al., 1983)
form  Tan to white crystalline solid
Water Solubility  (mg/L):
7.600 at 24 °C (shake flask-nephelometry, Hollifield, 1979)
2.7 at 20–25 °C (Kilzer et al., 1979)
Merck  13,2098
Henry's Law Constant (x 10-2 atm?m3/mol): 3.11 at 25 °C (approximate - calculated from experimentally determined water solubility and vapor pressure values)
Exposure limits NIOSH REL: TWA 1 mg/m3.
IARC 2B (Vol. 20, Sup 7) 1987
EPA Substance Registry System Chlordecone (143-50-0)

Safety Data

Hazard Codes  T,N
Risk Statements 
Safety Statements 
RIDADR  2761
RTECS  PC8575000
HazardClass  6.1(b)
PackingGroup  III
Hazardous Substances Data 143-50-0(Hazardous Substances Data)
Toxicity
LD50 orally in rats: 125 mg/kg (Gaines)

Hazard Information

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