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Glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states.

Increased circulating levels of L-alpha-lysophosphatidylinositol (LPI) are associated with cancer and LPI is a potent ligand for the G-protein-coupled receptor GPR55.''Lysophosphatidylinositol (LPI) has the ability to modulate cancer cell migration. It can control the functions of endothelium. LPI can serve as an autocrine regulator of cell growthhence its known to participate in cancer progression. It can stimulate signaling cascadesth at are essential for survivalmigration and proliferation of cells.