AS2690168 hydrochloride is an orally active RANKL signal transduction inhibitor which suppresses RANKL-induced osteoclastogenesis of RAW264 cells. AS2690168 can be utilized in research related to pathological osteolysis[1].
References
[1] Morikawa N, et al. Pharmacological characterization of AS2690168, a novel small molecule RANKL signal transduction inhibitor. Eur J Pharmacol. 2022 Jun 5;924:174941. DOI:10.1016/j.ejphar.2022.174941