13194-48-4

Ethorop is one of a family of organophosphorus pesticides. ETHOPROPHOS(13194-48-4) is combustible though ETHOPROPHOS(13194-48-4) may require some effort to ignite. ETHOPROPHOS(13194-48-4) is very toxic by skin absorption and inhalation. ETHOPROPHOS(13194-48-4) may or may not be water soluble.

Organothiophosphates, such as ETHOPROPHOS, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Hydrolyzed in alkali.

This material is extremely toxic; the probable oral lethal dose for humans is 5-50 mg/kg, or between 7 drops and 1 teaspoonful for a 150 lb. person. It is a cholinesterase inhibitor which affects the nervous system.

A potential danger to those involved in the manufacture, formulation and application of this nematocide and soil insecticide

(Non-Specific--Organophosphorus Pesticide, Liquid, n.o.s.) Container may explode in heat of fire. Fire and runoff from fire control water may produce irritating or poisonous gases. Stable in water. Hydrolyzed in alkali.

If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Speed in removing material from skin is of extreme importance. Shampoo hair promptly if contaminated. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. Remove and isolate contaminated clothing and shoes at the site. Keep victim quiet and maintain normal body temperature. Effects may be delayed; keep victim under observation

UN3018 Organophosphorus pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, and epoxides. Strong oxidizers may cause release of toxic phosphorus oxides. Organophosphates, in the presence of strong reducing agents such as hydrides, may form highly toxic and flammable phosphine gas. Keep away from alkaline materials

Introduced in the 1960s, ethoprop is a nonsystemic insecticide/nematicide. The mobility of ethoprop in soil and its half-life are strongly dependent on soil organic matter (21). It is not known to be carcinogenic and is available as granules or emulsifiable concentrates.

Clear Colorless Oil

Ethoprophos is a pale yellow liquid.

In accordance with 40CFR 165 recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office

Ethoprophos is an organophosphate non-systemic nematicide and soil insecticide. Ethoprophos is an acetylcholinesterase (AChE) inhibitor.

Ethoprophos is used to control plant parasitic nematodes and soil insects.

Insecticide; nematocide.

Nonsystemic, nonfumigant nematocide and soil insecticide for control of insects in ornamentals, potatoes, sweet potatoes, tomatoes, strawberries, bananas, pineapples, sugar cane, turf and many other crops.

ChEBI:Ethoprophos is an organic thiophosphate and an organothiophosphate insecticide. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an agrochemical and an antinematodal drug.

Nematicide, Insecticide: Ethoprop is used as a pre-plant soil application to control wireworms and nematodes in potatoes, sugar cane, sweet potatoes, and tobacco, with lesser usage on corn (field and sweet), beans (lima and snap), cucumbers, and cabbage. In addition, it is used to treat pineapples, bananas, and plantains, as well as fieldgrown ornamentals and non-bearing citrus trees, and commercial turf. Roughly 60% of ethoprop is applied to potatoes.

AI3-27318®; CASWELL No. 434C®; JOLT®[C]; MENAP®; MOBIL V-C 9-104®; MOCAP®[C]; MOCAP 10G®[C]; PHOSETHOPROP®; ROVOKIL®; V-C 9-104®[C]; V-C CHEMICAL V-C 9-104®[C]; VIRGINIA-CAROLINA VC 9-104®

In a combined chronic feeding/ carcinogenicity study, when rats were fed diets with 0, 1, 10, or 100 ppm ethoprop in the diet for 24 months (equivalent to 0, 0.041, 0.40, or 4.19 mg/kg/day (males); 0, 0.052, 0.51, or 5.12 mg/kg/day (females)), adrenal gland malignant pheochromocytomas were increased in males and thyroid C-cell carcinomas were increased slightly in males . When ethoprop was administered in the diet to mice for 104 weeks at 0, 0.2, 2.0, or 30 ppm (males: 0, 0.026, 0.254, or 3.96 mg/ kg/day; females: 0, 0.032, 0.318, or 4.9 mg/kg/day), survival was unaffected at any dose level and no statistically significant dose-related incidence of tumors were seen in males or females.

Soil. The reported half-life in humus-containing soil (pH 4.5) and a sandy loam (pH 7.2–7.3) are 87 and 14–28 days, respectively (Hartley and Kidd, 1987). The rate of degradation increased in soils that had been treated annually four times (Smelt et al., 1987).
Chemical/Physical. Emits toxic fumes of phosphorus and sulfur oxides when heated to decomposition (Sax and Lewis, 1987).

Ethoprophos is a soil-acting insecticide and nematicide which is generally incorporated into the soil in the form of a granular formulation. Volatilisation is a factor involved in the loss and movement of the compound in the environment. The major route of degradation of ethoprophos in both plants and mammals is via hydrolysis to give O-ethyl S-propyl phosphorothioate through loss of propanethiol. Propanethiol has been shown to react as a nucleophile to yield ethyl propyl sulfide through attack on the phosphorus atom and dipropyl disulfide through attack on the sulfur atom of ethoprophos. The sulfide metabolites are further metabolised via oxidation to sulfoxides and sulfones. In mammals, an additional important route of detoxification is through de-ethylation via glutathione- S-alkyl transferase, a route common to many organophosphorus insecticides.

Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool, well-ventilated area. Where possible, automatically pump liquidfrom drums or other storage containers to processcontainers.

Ethoprophos is very stable in neutral and weakly acidic media but it is hydrolysed rapidly in alkaline solutions (PM). The DT₅₀ of ethoprophos in 0.05M NaOH solution at 25 °C was 35 min and the hydrolysis product was identified as O-ethyl S-propyl phosphorothioate (2), indicating the greater susceptibility of the P-S bond to hydrolysis over the P-O bond. There was no measurable hydrolysis in 0.1M HCl after 1 hour (Menzer et al., 1971). The route of the base-catalysed hydrolysis of ethoprophos is shown in Scheme 1.