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MDL 27399 inhibits human neutrophil cathepsin G.

MDL 27399 is an inhibitor of human neutrophil cathepsin G (Ki = 7 μM). MDL 27399 can be used for research of inflammatory diseases[1].

[1] N.S. Doherty, et al. Novel inhibitors of polymorphonuclear neutrophil (PMN) elastase and cathepsin G: Evaluation in vitro of their potential for the treatment of inflammatory connective tissue damage. International Journal of Immunopharmacology. Volume 12, Issue 7, 1990, Pages 787-795