Fasciculic acid B is the ester of fasciculol B & 3-hydroxy-3-methylglutaric acid; calmodulin antagonist from mushroom Naematoloma fasciculare.
Uses
Fasciculic acid B is a steroid that can be isolated from Hypholoma lateritium. Fasciculic acid B has antiinflammatory and calmodulin antagonistic activity[1][2].
Definition
ChEBI: Fasciculic acid B is a triterpenoid.
References
[1] Ványolós A, et al. Extracts and Steroids from the Edible Mushroom Hypholoma lateritium Exhibit Anti-Inflammatory Properties by Inhibition of COX-2 and Activation of Nrf2. Chem Biodivers. 2020 Sep;17(9):e2000391. DOI:10.1002/cbdv.202000391 [2] Takahashi A, et al. Fasciculic acids A, B and C as calmodulin antagonists from the mushroom Naematoloma fasciculare. Chem Pharm Bull (Tokyo). 1989 Dec;37(12):3247-50. DOI:10.1248/cpb.37.3247
