1251957-89-7

Magmas-IN-1 (compound 9) is a small molecule Magmas inhibitor (SMMI). Magmas is mitochondria associated，granulocyte-macrophage colony stimulating factor signaling molecule，as well as a GM-CSF inducible gene in myeloid cells. Magmas-IN-1 inhibits Magmas and modulates mitochondrial function. Magmas-IN-1 also inhibits proliferation in yeast at 4 μM[1].

[1] Jubinsky PT, et al. Design, synthesis, and biological activity of novel Magmas inhibitors. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3479-82. DOI:10.1016/j.bmcl.2011.03.050