1242169-24-9

PC407-ws is a water-soluble novel potential COX-2 inhibitor.

COX-2-IN-50 is a water-soluble COX-2 inhibitor with significant analgesic activity. The solubility of COX-2-IN-50 in water reaches 20.3 mg/mL, far exceeding the 1.6 μg/mL of its precursor compound PC407. COX-2-IN-50 demonstrates good biocompatibility and is suitable for the development of injectable dosage forms. COX-2-IN-50 has proven its analgesic effect in vivo and shows potential application value[1].

[1] Enhanced water-soluble derivative of PC407 as a novel potential COX-2 inhibitor injectable formulation